This question is a bit particular and I would say I can only decide case-by-case. I suppose I would accept, if the fact that he's represented in that way had a reason or made sense in some way. Anyway there is an "Asimov Inspired" folder, that is specifically made for non-canon creations that are still set in Asimov's universe or have some degree of affinity with it. I think that in most cases there would be no problem to accept different interpretations of canon characters in that folder, as long as the general idea of Asimov's universe is intact. (even crossovers can be accepted, if the Asimovian part is clearly recognizable)